March 1968

The Original Illustrations of Hodgkin's Disease

Author Affiliations

Portland, Ore

From the Department of Pathology, University of Oregon Medical School, Portland.

Arch Intern Med. 1968;121(3):288-290. doi:10.1001/archinte.1968.03640030080014

Thomas Hodgkin's now classical paper "On Some Morbid Appearances of the Absorbent Glands and Spleen" was read before the Medico-Chirurgical Society of London in January 1832.1 After describing six of his own cases, Hodgkin wrote:

Whilst examining the unrivalled collection of pathological drawings made by my friend Dr. Carswell, I was struck with one representing a greatly enlarged spleen, loaded with large tubercles of a rounded figure and light colour. I immediately recognized it as a fine example of the affection I have been describing....

Carswell saw his case at the Hospital St. Louis, Paris, in April 1828, described it in his notebook2 under the title "Cancer Cerebriformis of the Lymphatic Glands and of the Spleen," and painted five plates in water color to illustrate the pathological features. These fine paintings, the earliest known color pictures of the morbid anatomy of Hodgkin's disease, were on display while Hodgkin

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