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May 1968

Hemophilus InfluenzaeBronchopneumonia in Adults

Author Affiliations


From the Detroit General Hospital and the departments of medicine, microbiology, and pathology, Wayne State University School of Medicine, Detroit. Doctor Tillotson is now at the Harvard Medical School, Boston.

Arch Intern Med. 1968;121(5):428-432. doi:10.1001/archinte.1968.03640050038008

Two distinct types of Hemophilus influenzae pneumonia occur. In both, an antecedent upper respiratory infection may be important. Lobar or segmental pneumonias affect persons without previous lung disease. These are type b infections. Abscess, empyema, or pleural fibrosis may occur. Mortality is related to meningitis which may follow bacteremia. The increasingly common second type is a moderate diffuse miliary bronchopneumonia affecting middle-aged to elderly persons with chronic lung disease. Myalgias and absence of fever are often striking. Cigarette smoking is an underlying factor. Smooth strains (types a-f) as well as nontypable rough forms are involved. Intrathoracic complications are rare. Rather than the results of acute pneumonia, deaths mirror severity of previous lung or cardiac disease. Ampicillin or the tetracyclines are the antimicrobial drugs of choice.