By Irving M. Ariel, MD, FACS. Price, $15.75. Pp 375. Grune & Stratton, Inc., 381 Park Ave S, New York 10016, 1966.
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This volume is a collection of reviews primarily by surgeons from New York and Minnesota dedicated to Dr. Owen H. Wangensteen, their teacher. Dr. Irving M. Ariel has edited these into a readable and coordinated form that provides a current review for the physician interested in cancer. This type of volume is not too helpful for the average practitioner but provides a current reference source for the hospital library.
Dr. Harris Busch, from the Department of Pharmacology at Baylor University, provides a worthwhile chapter on the molecular biology of cancer. The discussion on blood flow to tumors is a study with radioactive microspheres where in 14 human carcinomas the postinjection concentration of normal to tumor tissue varied from 2.5:1 up to 30:1. If it is true that chemotherapeutic drugs are not specific but randomly effect any cell in deoxyribonucleic acid synthesis, then this information on poor blood supply in cancer
Korst DR. Progress in Clinical Cancer, vol 2.. Arch Intern Med. 1968;121(5):484-485. doi:10.1001/archinte.1968.03640050094037