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June 1968

Acute Glomerulonephritis.

Author Affiliations

Tacoma, Wash

Arch Intern Med. 1968;121(6):580. doi:10.1001/archinte.1968.03640060094034

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This book is the published proceedings of the 17th Annual Conference on the Kidney sponsored by the National Kidney Foundation and held on Oct 7 to 9, 1965. It is a patchwork quilt of new and old material concerning many aspects of glomerulonephritis prepared by multiple authors.

Clinicians will most appreciate "Physiologic Aspects of Acute Glomerulonephritis" and "Therapy of Acute Glomerulonephritis." The difficulties of attempting to correlate abnormalities of renal function and histology in glomerulonephritis are well presented, and the point "that glomerulonephritis is really a total nephron disease" is underscored. This conclusion is not surprising in the light of the "intact nephron hypothesis" as proposed by Bricker in recent years. While this concept is alluded to in discussion, more extensive interpretation of reported observation in terms of this hypothesis would have been interesting.

Both the extent and limits of present knowledge of physiologic abnormalities in acute glomerulonephritis are well

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