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July 1968

Fundamentals of Neuropathology, ed 2.

Arch Intern Med. 1968;122(1):87-88. doi:10.1001/archinte.1968.00300060089031

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Santiago Ramón y Cajal spoke of the "bewitchment of the infinitely small" underlying his incessant striving to clarify the bewildering ramifications of neurohistology. Do pathologists feel aggrieved when they view the distortions wrought by disease on the beautiful "cellscapes" under their lenses? Presumably they find a compensating fascination in mechanisms of repair just as clinicians viewing, say, cerebellar ataxia see not a parody of normal movement but a sorrowful testimony of an absent synergism taken for granted by the healthy; or they may experience a detective's delight in checking the fingerprints of disease, just as clinicians elicit quite sinister physical signs with almostpleasurable detachment if they provide diagnostic information. Certainly Dr. Dublin's well-informed treatise on neuropathology, now in its second edition, is written in a manner suggesting total engrossment in his subject.

Without attempting to be exhaustive, he has dealt adequately with the pathology of the major nervous diseases and

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