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March 1969

Hypertriglyceridemia, Diabetes Mellitus, and Coronary Vessel Disease

Author Affiliations

Bethesda, Md

From the Molecular Disease Branch, National Heart Institute, National Institutes of Health, Bethesda, Md.

Arch Intern Med. 1969;123(3):220-228. doi:10.1001/archinte.1969.00300130002002

Hypertriglyceridemia, diabetes, and coronary vessel disease are often interdependent disorders. Hyperglyceridemia may be exogenous, endogenous, or mixed. It may be familial or secondary to a host of different disorders. The clinical and chemical differentiation of hyperglyceridemia is discussed as are the roles of glucose intolerance, insulin response, dietary carbohydrate and fat, and obesity in each type of hyperglyceridemia. Specific therapeutic approaches which are designed to ameliorate at least the chemical manifestations of these disorders are reviewed.