November 1969

Microradiographic Studies of Bone in Renal Osteodystrophy

Author Affiliations

Rochester, Minn; Los Angeles

From the Section of Orthopedic Research, Mayo Clinic and Mayo Foundation, Rochester, Minn (Dr. Jowsey); and Cedars-Sinai Medical Research Institute and the departments of medicine, Cedars-Sinai Medical Center; Veterans Administration Center; and UCLA School of Medicine, Los Angeles (Drs. Massry, Coburn, and Kleeman).

Arch Intern Med. 1969;124(5):539-543. doi:10.1001/archinte.1969.00300210021003

In the May 1968 issue of the American Journal of Medicine, Stanbury wrote an excellent and comprehensive review of bone disease in uremia.1 The present communication, therefore, is primarily concerned with the appearance of the bone in nine patients who had a variable history of renal disease, and with the findings related to some aspects of the patient's history. As far as possible, only new features which have arisen from the study will be described; some relevant data gleaned from associated studies will be mentioned to clarify features of renal osteodystrophy.

Materials and Methods  Nine uremic patients who were maintained for variable periods of time with peritoneal dialysis, hemodialysis, or both were studied. The pertinent clinical and laboratory data are shown in Table 1. The blood levels of calcium and phosphorus shown in Table 1 are those observed about the time the specimens of bone biopsy were obtained from

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