A review of 258 autopsy reports of aortic regurgitation seen during the past 36 years has revealed changes in the relative frequencies of the various causes of the lesion, in survival, and in causes of death, as well as in the type and frequency of coexistent forms of heart disease and in the incidence of rheumatic activity in the rheumatic cases.
Aortic regurgitation, although an "old" disease, is continuing to change.
Barondess JA, Sande M. Some Changing Aspects of Aortic Regurgitation. Arch Intern Med. 1969;124(5):600-605. doi:10.1001/archinte.1969.00300210082012