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December 1969

Pseudohypertrophic Muscular Dystrophy.

Arch Intern Med. 1969;124(6):774-775. doi:10.1001/archinte.1969.00300220126041

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Studies of Pseudohypertrophic Muscular Dystrophy (PMD) appeared in the series, American Lectures in Living Chemistry. Editor Kugelmass introduces this interesting and, in parts, rather provocative book as follows:

Dr. Bonsett of Indianapolis brings order, simplification and perspective to the unusual wasting pattern of pseudohypertrophic muscular dystrophy. In a long-term study, which begins in the clinic, he attacks the disease from the perspective of the various clinical sciences. In the present volume, the clinical features are correlated according to a set of fundamental principles with histological events, pathophysiological changes and the patient's age.

The author chose to concern himself only with the rapidly progressive variant of the X-linked muscular dystrophies (MD), the so-called pseudohypertrophic or Duchenne MD. He deliberately omits consideration of other MDs.

The book is divided into "Clinical" and "Basic Science." In a short historical summary (chapter 1), the contributions of Edward Meryon, Guillaume Duchenne (de Boulogne), and

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