March 1970

Cytomegalovirus Infection Associated With Cardiopulmonary Bypass

Author Affiliations

Los Angeles

From the Nephrology Section, Wadsworth Hospital, Veterans Administration Center; and the Department of Medicine, the Center for the Health Sciences, University of California, Los Angeles.

Arch Intern Med. 1970;125(3):488-492. doi:10.1001/archinte.1970.00310030098011

Five of six patients with the post-perfusion syndrome (PPS) following cardiopulmonary bypass had evidence of cytomegalovirus (CMV) infection. An additional patient who died in the immediate postoperative period had asymptomatic viruria preoperatively. One patient in whom postoperative lymphocytosis, hepatomegaly, and viruria developed had preoperative cytologic evidence of infection. In this study of 25 patients, the existence of latent infection prior to operation was suggested in this single patient. Nineteen other patients studied prospectively had no evidence of CMV infection or PPS.