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Ulcerative colitis is, as the authors point out, a most imprecise disease. Its etiology is not known, and various methods of treatment are necessarily empirical. In addition, if one is to obtain a good clinical picture of the affliction, other inflammatory conditions of the large and small bowel must be excluded in order to make accurate diagnoses and evaluations of the results of medical and surgical treatment. The authors have made an exhaustive, clearly written, and reasonable attempt to clarify diagnosis and treatment. Their considerable experience in managing ulcerative colitis is presented in a particularly enlightening fashion. Analysis of the pertinent literature, as well as their own results, is objective and well thought-out. Details of all aspects of ulcerative colitis are minutely and carefully examined, and conclusions are clearly set forth, backed by statistical validation.
These conclusions are heavily in favor of operative intervention in all patients 60 years of
Nelson RS. Ulcerative Colitis.. Arch Intern Med. 1970;125(4):730. doi:10.1001/archinte.1970.00310040154024