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February 1971

internal at large medicine

Arch Intern Med. 1971;127(2):193-204. doi:10.1001/archinte.1971.00310140021002

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200 180 140 100 60 20 UMBILICAL CORD BLOOD CHOLESTEROL (in mg/100 ml) IN 1660 CONSECUTIVE BIRTHS mean 63.3 ± 18.5 mg/100 ml 703 638 72 193 34 9 5 4 2

Premature atherosclerosis  As many as one of every 200 babies born in the US may have a genetic defect which is associated with severe premature atherosclerosis in later life. A mass screening program of umbilical cord blood could help to detect the disorder, Familial Type II hyperlipoproteinemia. Children with the condition could then be considered for treatment with diet, drugs, or both to prevent later arteriosclerotic disease.These were some of the findings presented at the recent 24th annual meeting of the American Heart Association's Council on Arteriosclerosis. Several investigators suggested treatment in early childhood, but they were wary of starting too early. "No one really knows," said Peter O. Kwiterovich, MD, "how brain growth would be affected

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