February 1971

Physiopathology and Therapy of Human Blood Disease.

Author Affiliations

USA Washington, DC


By E Kelemen, MD, DSc. Price, not listed. Pp 618, with many charts, figures, photos, and illustrations. Pergamon Press Inc, 122 E 55th St, New York 10523,1969.

Arch Intern Med. 1971;127(2):325-326. doi:10.1001/archinte.1971.00310140153044

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This volume is an interesting and informative compendium of hematologic subjects. While it is designed, by the author's statement, for clinical research workers or advanced students, it is, nevertheless, a text which should have wide appeal to internists and hematologists. It is well referenced up to 1967 and a "Further Reading Bibliography" is included for each chapter.

Subjects such as the origin of blood and immunocompetent cells, cell kinetics including turnover rates, pools and half-lives, radiation injury, autoimmune aspects of pernicious anemia, autoimmune hemolysis, platelet physiopathology, and chromosome abnormalities in hematologic disorders are covered in great and praiseworthy depth. However, such newer and important aspects of hematology as red blood cell 2-3 diphosphoglycerate and its relation to oxygen affinity, the sucrose hemolysis test for detection of complement-sensitive red blood cell populations, the Epstein-Barr virus as related to lymphoma and infectious mononucleosis, factor XIII and its relation to coagulation, and modern

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