May 1971

Inhalation Carcinogenesis.

Author Affiliations

Harlingen, Tex


By M G Hanna, Jr, MD; P Nettesheim, MD; J R Gilbert, MD. Price. $3. Pp 524. Clearinghouse for Federal Scientific and Technical Information, National Bureau of Standards, US Department of Commerce, Springfield, Va 22131, 1970.

Arch Intern Med. 1971;127(5):968. doi:10.1001/archinte.1971.00310170176038

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This valuable paperback, No. 18 in the AEC Symposium Series, considers the inhalation carcinogenesis aspect of man's deteriorating relationship with his environment. It documents the proceedings of the Conference on Inhalation Carcinogenesis which was held in October 1969 by the Biology Division, Oak Ridge National Laboratory and sponsored by the National Cancer Institute and the AEC.

Considerable study of carcinogenesis from the inhalation of radioactive particles has been performed during the last 30 years; the expertise and systems developed for this work are now being applied to the study of nonradioactive physical inhalants. To determine whether a biological effect is linear or threshold, especially in low pollutant concentrations, is a formidable task better appreciated after perusal of the elaborate techniques and massive programs described in this volume.

The primary purpose of the conference was to evaluate animal inhalation experiments and techniques as models for the study of human respiratory carcinogenesis.

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