September 1971

Diagnostic Histochemistry.

Author Affiliations

Madison, Wis


By Frederick T Zugibe, MD, PhD. Price, $15.85. Pp 366, with 41 illustrations. CV Mosby Co, 3207 Washington Blvd, St. Louis 63103, 1970.

Arch Intern Med. 1971;128(3):478. doi:10.1001/archinte.1971.00310210154034

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The field of histochemistry has grown rapidly in recent years, reflecting the growth of its sister disciplines, biochemistry, molecular biology, and ultrastructure morphology. While several handbooks and stain formularies are available, pathologists and investigators have had need of an adequate reference in histochemistry. Diagnostic Histochemistry is an important new work which should receive wide acclaim in the area of laboratory medicine. The major strength of the book is the author's ability to describe specific procedures understandably and to discuss their merits and shortcomings objectively. The text is comprehensive, but not encyclopedic. The reader soon realizes that Zugibe has expended considerable thought and laboratory time in evaluating and analyzing procedures; he has translated broad personal experience into the pages of this textbook.

There are three major sections in the book. The first deals with the theoretical considerations of tissue processing and identification of components. Separate chapters deal with the lipids, carbohydrates,

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