January 1973

Deposition of Aerosols in Pulmonary Disease

Author Affiliations


From the Department of Medicine, University of Illinois Abraham Lincoln School of Medicine, Chicago. Dr. Goldberg is now with the Department of Radiology, University of Chicago.

Arch Intern Med. 1973;131(1):88-91. doi:10.1001/archinte.1973.00320070084009

Pathological conditions may possibly affect the deposition of aerosols in the human respiratory tract. Respiratory disease may cause alterations in the pattern of breathing and changes in airway diameter and geometry. These alterations may influence the main mechanisms of deposition—inertial impaction, gravitational sedimentation, Brownian diffusion, and turbulent diffusion.