[Skip to Content]
[Skip to Content Landing]
February 1973

Progressive Hereditary NephropathyA Variant of Medullary Cystic Disease?

Author Affiliations

New York

From the Department of Medicine, Cornell University Medical College, and the Department of Medicine, Division of Nephrology, New York Hospital-Cornell Medical Center. Dr. Wrigley is now at the Department of Medicine, Strong Memorial Hospital, Rochester, NY. Dr. Ennis is now at the Department of Medicine, University Hospital, Boston.

Arch Intern Med. 1973;131(2):240-244. doi:10.1001/archinte.1973.00320080076010

This report describes a kindred with progressive hereditary nephropathy. The disease is characterized by an insidious onset in the fourth and fifth decades of life, slow progression, normal results of urinalysis, and renal corticomedullary cysts. There is no salt wasting or severe anemia. Genetic transmission appears to be autosomal dominant. The family reported here may represent a new hereditary nephropathy or a variant of medullary cystic disease.