March 1973

Chemotherapy of Hodgkin's Disease in Studies by Acute Leukemia Group B

Author Affiliations

Copenhagen; Buffalo

From the Department of Internal Medicine, Finsen Institute, Copenhagen (Dr. Nissen); Department of Medicine B, Roswell Park Memorial Institute New York State Department of Health (Dr. Stutzman) and the Acute Leukemia Group B Operations Office, Buffalo (Dr. Holland and O. Glidewell).

Arch Intern Med. 1973;131(3):396-401. doi:10.1001/archinte.1973.00320090086010

Clinical trials of disseminated Hodgkin's disease were carried out during the last ten years by Acute Leukemia Group B. A gradual development of intensification of therapy has taken place from unmaintained singleagent treatment to intensive multiple-agent therapy followed by long-term maintenance, with corresponding improvement of frequency and duration of remissions.