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May 1973

Bone Marrow and Bone Tissue: Color Atlas of Clinical Histopathology.

Arch Intern Med. 1973;131(5):755. doi:10.1001/archinte.1973.00320110139026

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This atlas is a welcome change from the usual run, most of which could have been written 25 and 30 years ago. It represents a complete break with tradition for two major reasons.

First, the author has dropped the use of marrow smears completely, and relies on marrow sections, utilizing a highly refined methacrylate embedding technique obviously far superior to the routine paraffin embedding technique.

Secondly, he has broken down the age-old distinction, which is arbitrary and illogical, between the bone marrow on one hand and the bone and supporting tissues on the other.

There is an excellent section on bone tissue and diseases of the structure of the bone itself, something never considered in other atlases of the bone marrow.

Analysis of bone marrow in sections requires not only adequate histopathologic technique, but also good illustration requiring fine reproduction. This atlas is outstanding and clearly surpasses any prior

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