Bacteremia occurred during the six-hour period following consecutive liver biopsies. Blood was obtained immediately prior to, 15 minutes after, and two, four, and six hours after biopsy. A multiple culture system using liquid and solid media under aerobic and anaerobic conditions was used.
Observed incidence of bacteremia was 5.8% (4 of 69). Corrected incidence of asymptomatic gram-negative bacteremia was 2.9% (2 of 69). All liver biopsy cultures from bacteremic patients were sterile. We recommend obtaining blood cultures before liver biopsy if there is a history compatible with biliary or gastrointestinal tract infection. Shock, confusion, fever, or hypothermia occurring after liver biopsy may represent bacteremia rather than hemorrhage or sterile biliary peritonitis.
McCloskey RV, Gold M, Weser E. Bacteremia After Liver Biopsy. Arch Intern Med. 1973;132(2):213-215. doi:10.1001/archinte.1973.03650080057011