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August 1973

Tropical Sprue and Megaloblastic Anaemia.

Author Affiliations

Washington, DC

Arch Intern Med. 1973;132(2):298-299. doi:10.1001/archinte.1973.03650080140036

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This is a book that will be cited for many years as a classic reference source for tropical sprue. It provides a clinical description of the disease as it exists in various parts of the world. The observations are recorded by the original investigators and are not merely recitations of the findings of others. Unlike most multiauthored texts, the contributions are largely the result of 13 years of prospective collaboration among workers in England, India, Southeast Asia, and East Africa. A contribution is included from the Americas that describes tropical sprue in Haiti and among Puerto Rican immigrants to New York. The individual reporting of similar work from five laboratories provides some repetition but permits excellent comparison of findings from different geographic areas.

The contents include an introductory section delineating the objectives for the collaborative study and an exposition of methods used for patient selection, therapeutic trials, and laboratory techniques.

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