October 1973

Mental Retardation.

Author Affiliations

Burlington, Vt.


By Lewis B. Holmes, MD. Price, $28. Pp 430. Macmillan Co, 866 Third Ave, New York 10022, 1972.

Arch Intern Med. 1973;132(4):626. doi:10.1001/archinte.1973.03650100134036

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Several similar volumes have appeared in recent years and have proved to be most helpful and quite popular with physicians and investigators interested in or dealing with children and adults afflicted with one of the many forms of mental retardation.

This atlas reflects the fantastic development that has occurred within the last few years in the elucidation of the pathogenetic mechanisms underlying a number of syndromes characterized by abnormal mental development.

This particular contribution is by far the most complete and certainly the most informative I have encountered.

One-hundred seventy-three syndromes are described briefly and illustrated. All of them have several photographs, ranging from pictures of patients, characteristic radiologic abnormalities, and pathognomonic pathologic material to diagnostic karyotypes and other specific features.

In each instance, the discussion, which is brief and to the point, touches upon physical features, nervous system aspects, pathological findings, treatment and prognosis, genetics, and differential diagnosis.

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