Twelve patients had acute blastomycotic arthritis without evidence of adjacent osteomyelitis. The method of spread appeared to be hematogenous. All patients in this series had pulmonary involvement, and 11 had skin lesions. The diagnosis was established by microscopic examination of the joint fluid and confirmed by culture. Intravenous administration of amphotericin B was the treatment of choice.
Fountain FF. Acute Blastomycotic Arthritis. Arch Intern Med. 1973;132(5):684-688. doi:10.1001/archinte.1973.03650110040008