January 1974

Progress in Medical Genetics.

Author Affiliations

Los Angeles


Edited by Arthur G. Steinberg, PhD, and Alexander G. Bearn, MD. Price, $19.50. Pp 319. Grune & Stratton Inc, 111 Fifth Ave, New York 10003, 1972.

Arch Intern Med. 1974;133(1):156-157. doi:10.1001/archinte.1974.00320130158017

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Consideration of this volume has been one of my more pleasant tasks in recent weeks. Some criticisms will be made, but, on the whole, the value of the book for the generalist or specialist is considerable.

Fenner and White's first chapter ("Genetic Aspects of Viral Diseases of Animals") is well written. The first section, concerned with viral genetics, recombination, and transcription, is probably not suitable for most physicians. The succeeding sections are relevant.

In general, this chapter seems to be a paraphrasing of Fenner and White's "Medical Virology," which I consider better organized and phrased, particularly for the physician. Compare, for example, the explanation of "genetic drift," which is clear in Fenner and White and ambigious in the present volume.

German's chapter on "Genes Which Increase Chromosomal Instability in Somatic Cells and Predispose to Cancer" is one of the most thought-provoking of the volume. Unfortunately, (or perhaps to be

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