February 1974

Kaposi Sarcoma in Kidney Transplant Recipients

Author Affiliations

Petah Tikvah, Israel

From the Department of Medicine C, the Renal Unit, Department of Pathology, and the Protein Laboratory, Beilinson Medical Center, TelAviv University Medical School, Israel. Dr. Myers is now Head of the Renal Unit, Meir Hospital, Kfar Saba, Israel.

Arch Intern Med. 1974;133(2):307-311. doi:10.1001/archinte.1974.00320140145017

A growing experience with tumors of lymphoreticular origin in patients immunosuppressed to prolong homograft survival has been reported by Penn et al.1,2 In their most recent report,3 these authors have collected data on 17 such tumors reported from various centers, including their own. The predominant lymphoreticular malignant tumor was reticulum cell sarcoma, which accounted for 12 of the 17 cases, with a seeming predilection for an intracerebral situation. Three cases of Kaposi sarcoma are included in this group, of which two are from our practice. The third case was of the visceral variety, and the case records have been recounted in detail by Siegal et al.4 This article describes in detail the natural history of our two Kaposi sarcoma patients following intensive immunosuppressive therapy after renal transplantation.

Patient Summaries 

Patient 1.  —A 36-year-old woman had been found to have proteinuria in 1955 during an investigation for

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