A growing experience with tumors of lymphoreticular origin in patients immunosuppressed to prolong homograft survival has been reported by Penn et al.1,2 In their most recent report,3 these authors have collected data on 17 such tumors reported from various centers, including their own. The predominant lymphoreticular malignant tumor was reticulum cell sarcoma, which accounted for 12 of the 17 cases, with a seeming predilection for an intracerebral situation. Three cases of Kaposi sarcoma are included in this group, of which two are from our practice. The third case was of the visceral variety, and the case records have been recounted in detail by Siegal et al.4 This article describes in detail the natural history of our two Kaposi sarcoma patients following intensive immunosuppressive therapy after renal transplantation.
—A 36-year-old woman had been found to have proteinuria in 1955 during an investigation for
Myers BD, Kessler E, Levi J, Pick A, Rosenfeld JB. Kaposi Sarcoma in Kidney Transplant Recipients. Arch Intern Med. 1974;133(2):307-311. doi:10.1001/archinte.1974.00320140145017