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July 1975

Bilateral Deep Brachial Vein Thrombophlebitis Due to Vibrio fetus

Author Affiliations

From the Department of Medicine, University of Miami School of Medicine, and Miami Veterans Administration Hospital, Miami, Fla.

Arch Intern Med. 1975;135(7):994-995. doi:10.1001/archinte.1975.00330070116021

Since 1947, when Vinzent et al1 first published descriptions of human disease due to Vibrio fetus (Campylobacter fetus), more than 80 cases have been reported in the world's literature.2-6 The series of Vinzent et al consisted of three pregnant women with the organism isolated from blood. Two of the three aborted. Prior to this report, Vibrio fetus was considered a pathogen only of cattle and sheep; indeed, it had been well known as an important cause of infectious abortion in these animals.7 Nonetheless, infections with Vibrio fetus in humans are not restricted to pregnancy; rather, among adults, infection has been recorded almost three times more often in men than in women, and 75% of all cases are in patients older than 45 years.2 In addition, multiple sites of infection have been found, eg, central nervous system, joints, endocardium, lung, and in several cases, vascular endothelium. This

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