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June 1977

Histiocytic Lymphoma of B Cell Origin

Author Affiliations

From the Department of Medicine and Division of Clinical Pathology, State University of New York, Upstate Medical Center, Syracuse.

Arch Intern Med. 1977;137(6):800-803. doi:10.1001/archinte.1977.03630180072021

A histiocytic lymphoma with a terminal leukemic phase occurred in a 50-year-old man. Immunologic studies indicated that neoplastic cells from the peripheral blood sample, bone marrow aspirate, and lymph node carried surface immunoglobulin. Cytochemical and immunohistochemical analysis of this histiocytic lymphoma and its subsequent leukemic phase displayed a profile consistent with a lymphocytic rather than a histiocytic origin of the neoplastic cell.

(Arch Intern Med 137:800-803, 1977)