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September 1977

Disseminated Trichosporon capitatum Infection in an Immunosuppressed Host

Author Affiliations

From the Division of Infectious Diseases (Drs Winston and Linné), Department of Medicine, Clinical Laboratories (Mr Balsley and Ms Rhodes), and Department of Pathology (Mr Balsley and Ms Rhodes), University of California at Los Angeles, The Center for the Health Sciences.

Arch Intern Med. 1977;137(9):1192-1195. doi:10.1001/archinte.1977.03630210066020

Trichosporon is a frequent cause of superficial mycotic infections but has rarely been associated with invasive disease. A patient undergoing bone marrow transplantation who died from disseminated Trichosporon capitatum infection with endocarditis is reported, and the clinical spectrum of human infection caused by fungi of this genus is reviewed. To our knowledge, this is the first reported case of clearly invasive disease caused by this specific organism and emphasizes the expanding spectrum of unusual infections in the severely immunosuppressed patient.

(Arch Intern Med 137:1192-1195, 1977)