September 1977

Therapeutic Regimens for Anorectal Gonococcal Infection in Males

Author Affiliations

From the Department of Medicine, Harbor General Hospital, Torrance, Calif (Drs Klein, Fisher, Chow, and Guze); the Research and Medical Services, Wadsworth Veterans Administration Hospital, Los Angeles (Dr Guze); and the University of California, Los Angeles, School of Medicine (Drs Chow and Guze).

Arch Intern Med. 1977;137(9):1234-1235. doi:10.1001/archinte.1977.03630210100029

Anorectal gonococcal infection is particularly prevalent in women and homosexual men. Although the currently recommended Public Health Service therapeutic regimens for uncomplicated gonorrhea appear to be effective also for anorectal gonorrhea in women, their efficacy for anorectal infection in men has not been adequately evaluated. We report a case of gonococcal proctitis in a homosexual man that did not respond to therapy with ampicillin plus probenecid and tetracycline, but subsequently responded to spectinomycin therapy. Currently available therapeutic regimens for anorectal gonococcal infection in males are reviewed.

(Arch Intern Med 137:1234-1235, 1977)