November 1977

Giant Kidneys in Waldenström's Macroglobulinemia

Author Affiliations

From the Departments of Medicine (Drs Grossman, Bia, Goldwein, and Goldberg) and Pathology (Dr Hill), Hospital of the University of Pennsylvania and the University of Pennsylvania School of Medicine, Philadelphia.

Arch Intern Med. 1977;137(11):1613-1615. doi:10.1001/archinte.1977.03630230085023

A patient with Waldenström's macroglobulinemia had the unique feature of having one kidney infiltrated with malignant cells to such an extent as to produce a large palpable abdominal mass. Other unusual aspects of this case include the destruction of renal tubules by the invading cells that resulted in interstitial fibrosis and was probably responsible for the appearance of whole IgM in the urine.

(Arch Intern Med 137:1613-1615, 1977)