A 50-year-old man who was a heroin addict developed bilateral, symmetrical swelling of the breasts as a result of injecting himself directly into the breasts for several years. Results of histologic examination of the breast tissue showed granulomatous inflammation and a foreign body reaction without gynecomastia or tumor. Liver and endocrine functions were generally normal.
(Arch Intern Med 138:483-484, 1978)
Carlson RH, Velez R, Rivlin RS. Pseudogynecomastia Secondary to Injection of Heroin Into Breast Tissue. Arch Intern Med. 1978;138(3):483-484. doi:10.1001/archinte.1978.03630270091031