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Article
April 1978

Agranulocytosis Secondary to Pentazocine Therapy

Author Affiliations

From the Department of Internal Medicine, Sections of Hematology and Oncology (Dr Greenberg), and Endocrinology (Dr Walter), University of California, Davis/Sacramento Medical Center. Dr Hoppin is with the Woodland Clinic Medical Group, Woodland, Calif.

Arch Intern Med. 1978;138(4):533-534. doi:10.1001/archinte.1978.03630280015010
Abstract

Agranulocytosis developed in three patients after prolonged oral pentazocine hydrochloride therapy. Two of the patients had a recurrence of their agranulocytosis within three weeks of reinstitution of pentazocine. Culture techniques in one patient indicate a probable metabolic effect.

(Arch Intern Med 138:533-534, 1978)

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