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April 1978

Endometrial Carcinoma Following Estrogen Therapy for Breast CancerReport of Three Cases

Author Affiliations

From the Departments of Medicine (Dr Khandekar) and Pathology and Laboratory Medicine (Dr Victor), Evanston Hospital; Northwestern University Medical School, Evanston, Ill; and Tuft's University Medical Cancer Unit, Lemmel Shattuck Hospital, Boston (Dr Mukhopadhyaya).

Arch Intern Med. 1978;138(4):539-541. doi:10.1001/archinte.1978.03630280021012

Three patients with metastatic breast cancer responded to diethylstilbestrol (DES) therapy, but later they developed endometrial carcinoma. Evidence is presented to support the hypothesis that endometrial carcinoma can occur in breast cancer patients receiving diethylstilbestrol therapy.

(Arch Intern Med 138:539-541, 1978)