August 1978

Chronic Renal Insufficiency From Cortical Necrosis Induced by Arsenic Poisoning

Author Affiliations

From the Nephrology Section, Department of Internal Medicine (Drs Gerhardt and Hudson), and the Department of Pathology (Drs Rao and Sobel), Medical College of Georgia, Augusta.

Arch Intern Med. 1978;138(8):1267-1269. doi:10.1001/archinte.1978.03630330067019

A 39-year-old man had anuria and azotemia and was found to be suffering from acute arsenic poisoning. After two peritoneal dialyses, partial renal function returned, and the patient has survived for five years without dialysis. Renal cortical necrosis was demonstrated by renal biopsy and renal calcification. We suggest that arsenic be added to the list of substances capable of causing renal cortical necrosis and recommend consideration of this complication in cases of arsenical poisoning.

(Arch Intern Med 138:1267-1269, 1978)