Two patients had adenocarcinoma of the stomach in association with common variable immunodeficiency syndrome. There has been an increased prevalence of malignancy in this late-onset immunodeficient state. Similar to five previously reported cases, our patients had gastric carcinoma as a late complication. Further documentation of this association stresses the need for long-term follow-up in this premalignant condition.
(Arch Intern Med 138:1682-1684, 1978)
Battle WM, Brooks FP. Adenocarcinoma of the Stomach With Common Variable Immunodeficiency Syndrome. Arch Intern Med. 1978;138(11):1682-1684. doi:10.1001/archinte.1978.03630360064025