Three cases are described in which hyperprolactinemia occurred as a feature of multiple endocrine adenomatosis, type 1 (MEA-1); enlargement of the sella turcica varied from gross to absent, and serum prolactin (PRL) levels ranged from 21 to 1,000 ng/ml in these cases. Since PRL-secreting pituitary tumors may occur with variable presentation in MEA-1, periodic measurements of serum PRL levels should be carried out to detect this abnormality.
(Arch Intern Med 138:1807-1808, 1978)
Carlson HE, Levine GA, Goldberg NJ, Hershman JM. Hyperprolactinemia in Multiple Endocrine Adenomatosis, Type 1. Arch Intern Med. 1978;138(12):1807-1808. doi:10.1001/archinte.1978.03630370027015