Severe, traumatic, cardiac, hemolytic anemia developed in a patient nine years after mitral valve replacement with a Starr-Edwards model 6120 prosthesis. Cardiac catheterization failed to demonstrate a perivalvular leak or prosthetic malfunction. Transfusion on two occasions resulted in accelerated hemolysis and failed to maintain an appreciable elevation of the hemoglobin level. At operation, a perivalvular leak was found. Replacement of the valve led to complete resolution of the hemolytic problem. The case demonstrates that cardiac hemolysis may be a good indicator of valve dysfunction.
(Arch Intern Med 139:374-375, 1979)
Weiss GB, Nienhuis AW, McIntosh CL, Klein HG. Traumatic Cardiac Hemolytic AnemiaA Late Complication of a Starr-Edwards Mitral Valve Prosthesis. Arch Intern Med. 1979;139(3):374-375. doi:10.1001/archinte.1979.03630400088032