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Article
April 1979

Thermoregulatory Failure Secondary to Acute IllnessComplications and Treatment

Author Affiliations

From the Department of Medicine, Veterans Administration Hospital, Little Rock, Ark. Dr Whittle is now with the Division of Cardiovascular Medicine, JHM Health Center, Gainesville, Fla.

Arch Intern Med. 1979;139(4):418-421. doi:10.1001/archinte.1979.03630410028012
Abstract

We report on six patients in whom hypothermia secondary to acute illnesses, including pneumonia, congestive heart failure, renal failure, drug overdose, and hypoglycemia, developed. Complications that occurred were metabolic acidosis in six patients, altered sensorium in five, bradyarrhythmia in three, and hyperamylasemia in two. All patients failed to demonstrate a shivering response and represent cases of acute thermoregulatory failure. Five of the six patients survived. In the course of treatment, the choice of active or passive rewarming should be based on whether or not normal thermoregulatory mechanisms are intact.

(Arch Intern Med 139:418-421, 1979)

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