May 1979

Cryofibrinogenemia in Henoch-Schönlein PurpuraReport of a Case

Author Affiliations


From the Rheumatology Section, Department of Medicine, David Grant USAF Medical Center, Travis Air Force Base, Calif (Drs Cwazka, Sprenger, and Naguwa) and the School of Medicine, University of California, Davis (Dr Birnberg).

Arch Intern Med. 1979;139(5):592-593. doi:10.1001/archinte.1979.03630420078026

A patient with Henoch-Schönlein purpura (HSP) had exacerbations of disease that correlated closely with the presence of cryofibrinogenemia. Cryofibrinogen was absent consistently during asymptomatic intervals. To our knowledge, such a pattern has not been described previously in typical HSP. We suggest that all patients with HSP be screened for cryofibrinogenemia during the active phase of disease to determine the incidence of this abnormality.

(Arch Intern Med 139:592-593, 1979)