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September 1979

Adult Bacteremic Haemophilus parainfluenzae InfectionsSeven Reports of Cases and a Review of the Literature

Author Affiliations

From Research and Medical Services, Veterans Administration Wadsworth Medical Center, Los Angeles (Drs Oill and Guze); Division of Infectious Disease, Department of Medicine, Harbor General Hospital, Torrance, Calif (Drs Chow and Guze); and the University of California at Los Angeles, School of Medicine (Drs Oill, Chow, and Guze). Dr Chow is now with the Division of Infectious Diseases, Department of Medicine, University of British Columbia, Vancouver.

Arch Intern Med. 1979;139(9):985-988. doi:10.1001/archinte.1979.03630460025011

Seven cases of adult Haemophilus parainfluenzae infections diagnosed by positive blood cultures are compared with cases previously reported in the English literature. Three patients had pneumonia, while the others had epiglottitis with meningitis, pharyngitis, arthritis, and endocarditis, respectively. Nonendocarditic manifestations of adult H parainfluenzae infection were reported in four other cases. In addition to the diseases of our patients, H parainfluenzae also has been isolated from cerebral abscesses. Patients did well with antibiotic therapy and there were no deaths. Report of antibiotic sensitivity testing of 50 strains disclosed 6% of isolates resistant to ampicillin sodium, with all sensitive to chloramphenicol. If the antibiotic sensitivity of the organism is unknown, then chloramphenicol therapy should be instituted until adequate susceptibility studies have been performed. If the organism is sensitive to ampicillin, then this is the drug of choice.

(Arch Intern Med 139:985-988, 1979)