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January 1980

Pathologic Rupture of the Spleen in Non-Hodgkin's Lymphoma

Author Affiliations

From the Departments of Internal Medicine (Drs Andrews, Hernandez, and Williams) and Pathology (Dr Grafton), Louisiana State University School of Medicine in Shreveport.

Arch Intern Med. 1980;140(1):119-120. doi:10.1001/archinte.1980.00330130121029

• Pathologic rupture of the spleen was the signal event in the onset of diffuse histiocytic lymphoma in a young woman. The diagnosis of lymphoma was established only after one month of observation. In a review of clinical features of ten patients with pathologic rupture of the spleen due to lymphoma, spleen size was variable, and in four of ten patients a diagnosis of lymphoma had not been suspected previously. In addition to the patient described herein, only two of those previously described survived splenic rupture.

(Arch Intern Med 140:119-120, 1980)