• Testing for the histocompatibility antigen HLA-B27 has been suggested as a valuable diagnostic aid in patients with ankylosing spondylitis and associated spondyloarthropathies, and B27 typing is becoming more readily available commercially at a number of clinical pathology laboratories. A current evaluation of B27 typing as a diagnostic test is presented, together with some guidelines for the clinical application of this test in the diagnosis of certain rheumatic diseases.
(Arch Intern Med 140:177-180, 1980)
Khan MA. Clinical Application of the HLA-B27 Test in Rheumatic DiseasesA Current Perspective. Arch Intern Med. 1980;140(2):177–180. doi:10.1001/archinte.1980.00330140035015