A 62-year-old woman with chronic active hepatitis receiving immunosuppressive drugs was initially admitted with sepsis secondary to an intra-abdominal abscess caused by Klebsiella pneumoniae. She had a stormy course despite adequate antimicrobial therapy. Her postoperative course was further complicated by a fungal infection. Blood, urine, and sputum cultures were positive for Trichosporon. Antifungal therapy was given but her condition deteriorated and she died. At autopsy, a disseminated fungal infection was found. Diagnosis and management of such infections in the immunosuppressed host are difficult.
(Arch Intern Med 140:277-278, 1980)
Kirmani N, Tuazon CU, Geelhoed GW. Disseminated Trichosporon InfectionOccurrence in an Immunosuppressed Patient With Chronic Active Hepatitis. Arch Intern Med. 1980;140(2):277–278. doi:10.1001/archinte.1980.00330140135035