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March 1980

Parathyroid Hormone and 25-Hydroxycholecalciferol Levels in Hypercalcemia of Acute Renal Failure

Author Affiliations

From the Section of Metabolic and Endocrine Disease (Dr Weinstein) and the Section of Nephrology (Dr Hudson), Department of Medicine, Medical College of Georgia, Augusta.

Arch Intern Med. 1980;140(3):410-411. doi:10.1001/archinte.1980.00330150124029

• A 38-year-old man developed symptomatic hypercalcemia during the diuretic phase of acute renal failure secondary to rhabdomyolysis. Although early secondary hyperparathyroidism was documented, parathyroid hormone levels fell when hypercalcemia occurred. The 25-hydroxycholecalciferol level was normal on two separate occasions during the hypercalcemia. Remobilization of muscle calcium deposits during diuresis is proposed as the cause of the hypercalcemia in this syndrome.

(Arch Intern Med 140:410-411, 1980)