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May 1980

Discoid Lupus Erythematosus and Tuberculosis Simulating Systemic Lupus Erythematosus

Author Affiliations

From the Department of Medicine, Peoria School of Medicine, Peoria, Ill. Dr Barfield is now in Rheumatology Practice. Charleston, SC, and is Clinical Instructor in Medicine, Medical University of South Carolina.

Arch Intern Med. 1980;140(5):715-717. doi:10.1001/archinte.1980.00330170131041

• A patient with chronic discoid lupus erythematosus was admitted with fever, arthralgia, pleuropericarditis, and a history of leukopenia. He was initially believed to have systemic lupus erythematosus (SLE), but extensive evaluation showed negative immunologic studies and the presence of acid-fast organisms on pericardial biopsy specimens with cultures positive for Mycobacterium tuberculosis. Discoid lupus erythematosus patients with extracutaneous manifestations should be carefully studied for concurrent illness, especially when serologic evidence for SLE is negative.

(Arch Intern Med 140:715-717, 1980)