June 1980

Raynaud's Phenomenon and Thyroid Deficiency

Author Affiliations

From the Department of Medicine, Coney Island Hospital and State University of New York, New York. Dr Shagan is now with the Department of Medicine, School of Medicine, East Tennessee State University, Johnson City.

Arch Intern Med. 1980;140(6):832-833. doi:10.1001/archinte.1980.00330180106029

We describe a patient with panhypopituitarism whose only clinical symptoms were related to Raynaud's phenomenon. Previously described patients with Raynaud's phenomenon due to hypothyroidism had Hashimoto's thyroiditis, an autoimmune disease associated with multisystem autoimmune disorders. The occurrence of Raynaud's phenomenon in hypothyroidism without thyroiditis and its prompt disappearance with thyroid replacement therapy demonstrate that decreased thyroid function per se is a cause of this vasospastic syndrome. Raynaud's phenomenon may be an early clue to the diagnosis of hypothyroidism.

(Arch Intern Med 140:832-833, 1980)