June 1980

Legionnaires' Disease Associated With Rhabdomyolysis and Myoglobinuria

Author Affiliations

From the Infectious Disease Service Department of Medicine, Boston City Hospital. Dr Posner is now with the Department of Adult Medical Oncology, Sidney Farber Cancer Institute, Boston; Dr Caudill, the Department of Infectious Diseases, Boston University Medical Center; Dr Brass, the Department of Cardiology, Tufts-New England Medical Center, Boston; and Dr Ellis, the Department of Internal Medicine, Boston Veterans Administration Hospital.

Arch Intern Med. 1980;140(6):848-850. doi:10.1001/archinte.1980.00330180122038

We report a fatal case of Legionnaires' disease associated with myopathy, myoglobinuria, elevated creatine phosphokinase (CPK) level, and pneumonitis. The precise cause of skeletal muscle damage in this patient remains obscure. The association with Legionnaires' disease in this case supports the observation that the Legionnaires' organism has the potential for affecting multiple organ systems, including skeletal muscle. Elevated CPK levels and myoglobinuria in a patient with pneumonitis should suggest the diagnosis of Legionnaires' disease.

(Arch Intern Med 140:848-850, 1980)