September 1980

Treatment of Staphylococcal Infections-Reply

Author Affiliations


Arch Intern Med. 1980;140(9):1249-1250. doi:10.1001/archinte.1980.00330200125039

There were no statistical differences between the number of endocarditis patients in groups 1 and 2 (nine vs seven). We agree that endocarditis in drug addicts appears to be a relatively benign disease; however, our patient was sufficiently ill for his physicians to request special laboratory tests. Case 17, while not having a complicated course, did fulfull our criteria for endocarditis as outlined in the report. Using these criteria for the clinical diagnosis of bacterial endocarditis, we accurately predicted the presence of endocarditis found at autopsy in the four patients who died. In addition, patient 15 likely had endocarditis, as his blood cultures were persistently positive for 24 hours despite the absence of a heart murmur or evidence of peripheral emboli. The addition of case 15 as an episode of infectious endocarditis would then give nine such cases in group 1 and eight in group 2. Nolan and Beaty1 actually

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