• The safety and usefulness of ibuprofen (Motrin) were evaluated in 15 patients suffering from hemophilic arthropathy via a double-blind protocol with individual crossover. No significant increase in hemorrhagic episodes or alteration in platelet function was observed. A decrease in morning stiffness was noted in nine patients, and three decreased markedly their use of other pain medications. We conclude that ibuprofen represents a relatively safe agent for the management of discomfort caused by hemophilic arthropathy in a select group of hemophilic patients.
(Arch Intern Med 140:1583-1585, 1980)
Hasiba U, Scranton PE, Lewis JH, Spero JA. Efficacy and Safety of Ibuprofen for Hemophilic Arthropathy. Arch Intern Med. 1980;140(12):1583-1585. doi:10.1001/archinte.1980.00330230029010