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February 1981

Mesenteric Hyaline Plasma Cell Lymph Node Hyperplasia With Amyloid Deposits

Author Affiliations

From the Departments of Internal Medicine (Drs Garcia-SanMiguel, Rozman, and Nomdedeau) and Pathology (Dr Palacin), Faculty of Medicine Hospital Clinico y Provincial, Barcelona, Spain.

Arch Intern Med. 1981;141(2):261-263. doi:10.1001/archinte.1981.00340020123032

• Lymph node hyperplasia (mixed hyaline vascular and plasma cell type) of mesenteric localization in a young woman was accompanied by noticeable systemic manifestations—fever, highly increased sedimentation rate, anemia, and hypergammaglobulinemia—that disappeared after the tumor was removed. Perivascular deposits of amyloid material were found within the tumor and in the spleen. To our knowledge, this finding has not been previously reported. On the basis of earlier studies in the literature and other considerations, an immunologic disorder is proposed as the cause of both the general symptoms and the amyloid deposits.

(Arch Intern Med 141:261-263, 1981)